How much does Kalydeco cost?

Kalydeco (ivacaftor) was approved in 2012 for the roughly 3 percent of CF patients with the G551D gating mutation, arriving with a U.S. wholesale acquisition price of $294,000 per year per patient. Its annual list cost — what a person would pay without any plan discounts or insurance coverage — is now about $311,000.

Is Kalydeco available in the UK?

Is Kalydeco available in the UK? Kalydeco is available for use in the UK for people with CF over the age of four months with one of nine rare gating mutations (G551D, G178R, S549N, S549R, G551S, G1244E, S1251N, S1255P or G139D) and over the age of 6 months for people with the R117H mutation.

Why is Kalydeco so expensive?

The Journal Sentinel/MedPage Today story noted that the cost of Kalydeco is borne by taxpayers through Medicaid and other government programs and by the workers and companies that finance employee health insurance plans.

How much does Kalydeco cost per year?

In response, Vertex, the manufacturer, priced Kalydeco in the US at about $300,000 per patient per year of treatment following its Food and Drug Administration (FDA) approval in 2012 (Silverman 2017).

Is there a generic for Kalydeco?

Has a generic version of Kalydeco been approved? No. There is currently no therapeutically equivalent version of Kalydeco available in the United States. Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Kalydeco.

How expensive is cystic fibrosis?

Results: The mean annual health care cost for treating CF is US $15,571. Costs for patients with mild, moderate, and severe disease are US $10,151, US $25,647, and US $33,691, respectively. Lifetime health care costs are approximately US $306,332 (3.5% discount rate).

What Kalydeco does to the body?

Researchers designed Kalydeco to treat cystic fibrosis patients with this gating mutation. It works by keeping the CFTR gate open for longer at the cell surface. This eases the transport of salts and water in and out of cells to improve hydration and clear mucus.

What are the side effects of Kalydeco?

Common side effects of Kalydeco include:

• upper respiratory tract infection,
• headache,
• stomach pain,
• nausea,
• rash,
• acne,
• diarrhea,
• dizziness,

How much does kalydeco cost per pill?

The cost for Kalydeco oral tablet 150 mg is around $26,179 for a supply of 56 tablets, depending on the pharmacy you visit….Oral Tablet.

Does kalydeco increase life expectancy?

Researchers found that Kalydeco-treated CF patients had a significantly lower risk of death, pulmonary exacerbation, hospitalization, transplant, and prevalence of CF-related complications and pathological microorganisms, as well as improved lung function.

What are the risks of Kalydeco?

The most common side effects of KALYDECO include:

• headache.
• upper respiratory tract infection (common cold), including: sore throat. nasal or sinus congestion. runny nose.
• stomach (abdominal) pain.
• diarrhea.
• rash.
• nausea.
• dizziness.

What is the life expectancy with cystic fibrosis?

CF Foundation Patient Registry Based on 2019 Registry data, the life expectancy of people with CF who are born between 2015 and 2019 is predicted to be 46 years. Data also show that of the babies who are born in 2019, half are predicted to live to be 48 years or older.