What category/class is diltiazem?

Diltiazem is in a class of medications called calcium-channel blockers. It works by relaxing the blood vessels so the heart does not have to pump as hard. It also increases the supply of blood and oxygen to the heart.

What is Diltiazem HCL ER used for?

Diltiazem is used alone or together with other medicines to treat angina (severe chest pain) or hypertension (high blood pressure). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly.

What kind of pill is diltiazem?

Diltiazem is a calcium channel blocker that works in the same way as other calcium channel blockers to treat high blood pressure and angina. There are other medicines (as well as diltiazem) that are used to treat these conditions.

Is diltiazem and diltiazem hydrochloride the same?

These medicines both contain an active ingredient called diltiazem hydrochloride. The difference between these is that Cardizem CD is designed to release the active ingredient slowly so that it works over 24 hours and can be taken once a day (CD stands for “controlled delivery”).

Can you take vitamin D with diltiazem?

Avoid taking high doses of vitamin D with this heart medication. High doses of vitamin D can cause hypercalcemia, which increases the risk of fatal heart problems with digoxin. Diltiazem (Cardizem, Tiazac, others). Avoid taking high doses of vitamin D with this blood pressure drug.

Is diltiazem a dihydropyridine?

Diltiazem is an oral and parenteral non-dihydropyridine calcium channel blocker. It is used in many clinical scenarios as an antihypertensive, anti-arrhythmic, and as anti-anginal. FDA-approved indications include atrial arrhythmia, hypertension, paroxysmal supraventricular tachycardia, and chronic stable angina.

What are the side effects of diltiazem HCL ER?

Dizziness, lightheadedness, weakness, nausea, flushing, constipation and headache may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. To lower the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

Is cartia and diltiazem the same?

What is Cartia XT? Cartia XT (diltiazem) is a calcium channel blocker that is used to treat hypertension (high blood pressure) or angina (chest pain).

Does diltiazem make you pee?

Diltiazem did not cause tachycardia in either strain. Moreover, hypotensive doses of diltiazem acutely increased urinary excretion of sodium as well as urine volume in saline-loaded SHR and WKY.

Can I take vitamin B12 with diltiazem?

No interactions were found between diltiazem and Vitamin B12. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

What is the difference between non dihydropyridine and dihydropyridine?

The dihydropyridines are more vascular selective and the non-dihydropyridines are more myocardial selective and tend to reduce the heart rate. Further important differences are between short- and long-acting forms of the calcium channel antagonists.

What is the drug classification for diltiazem?

Diltiazem is an orally administered, nondihydropyri-dine calcium-channel blocker that is used for the treatment of hypertension and atrial fibrillation. According to the Biopharmaceutics Classification System (BCS), diltiazem is a Class I substance (1, 2), meaning that it is highly soluble and highly permeable.

What is the plasma level of desdesacetyl diltiazem?

Desacetyl diltiazem is also present in the plasma at levels of 10% to 20% of the parent drug and is 25% to 50% as potent as a coronary vasodilator as diltiazem. Minimum therapeutic plasma levels of CARDIZEM appear to be in the range of 50 to 200 ng/mL. There is a departure from linearity when dose strengths are increased.

What is a BCS Class IV drug?

BCS class IV compounds, in general, are problematic with both poor solubility and permeability. The following tables (see Tables 3.4-3.7) contain lists of drugs that are categorized as BCS classes I to IV.

How many milligrams of diltiazem are in a 30g tube?

Cream in a 30g aluminium tube containing diltiazem cream 2% w/w. A nominal dose of 450 mg cream contains diltiazem hydrochloride 20 mg/g delivering 8.5 mg diltiazem hydrochloride per application.