How long does zuclopenthixol stay in your system?

Zuclopenthixol decanoate is a depot injection which slowly releases zuclopenthixol into your body to prevent your symptoms from coming back. It is given every 1-4 weeks….About zuclopenthixol.

Is clopixol first or second generation?

Antipsychotics by generic name and key characteristics

Is zuclopenthixol long-acting?

A number of typical antipsychotic drugs (the decanoates of haloperidol, fluphenazine, flupenthixol and zuclopenthixol) are available as long-acting intramuscular depot preparations, given at intervals of 2–4 weeks.

Is zuclopenthixol the same as clopixol?

Zuclopenthixol is a first generation antipsychotic. It is also known by the trade name Clopixol, Clopixol Acuphase and Clopixol Concentrate.

How do you administer zuclopenthixol?

Indications and dose Test dose 100 mg, dose to be administered into the upper outer buttock or lateral thigh, followed by 200–500 mg after at least 7 days, then 200–500 mg every 1–4 weeks, adjusted according to response, higher doses of more than 500mg can be used; do not exceed 600 mg weekly.

How do you give zuclopenthixol?

The usual dosage range of zuclopenthixol decanoate is 200 – 500 mg every one to four weeks, depending on response, but some patients may require up to 600 mg per week. The maximum single dose at any one time is 600 mg. For example, 1200 mg every 2 weeks should not be given.

Is Zuclopenthixol typical or atypical?

First generation ‘typical’ antipsychotics such as zuclopenthixol are an older class of antipsychotic than second generation ‘atypical’ antipsychotics.

What class of drug is Zuclopenthixol?

Zuclopenthixol is a typical antipsychotic neuroleptic drug of the thioxanthene class. It mainly acts by antagonism of D1 and D2 dopamine receptors.

What class of drug is zuclopenthixol?

How do you give zuclopenthixol decanoate?

How do you draw up Abilify injections?

Slowly inject the Sterile Water for Injection into the vial containing the ABILIFY MAINTENA lyophilized powder (see Figure 10). Withdraw air to equalize the pressure in the vial by pulling back slightly on the plunger. Subsequently, remove the needle from the vial.

What is the generic name for zuclopenthixol?

Zuclopenthixol, also known as Zuclopentixol or Zuclopenthixolum, is an antipsychotic agent. Zuclopenthixol is a thioxanthene -based neuroleptic with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors. Major brands of zuclopenthixol are Cisordinol, Acuphase, and Clopixol.

What is the mechanism of action of action of zuclopenthixol?

Zuclopenthixol is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors. Zuclopenthixol is a typical antipsychotic neuroleptic drug of the thioxanthene class. It mainly acts by antagonism of D1 and D2 dopamine receptors.

How much zuclopenthixol decanoate should I take?

Zuclopenthixol decanoate, when given at a dose of 200 mg every 2 weeks, results, on average, in a steady-state zuclopenthixol serum concentration of approximately 10 ng/mL (25 nmol/L), when measured immediately prior to the next injection. Indications And Clinical Uses: For the management of the manifestations of schizophrenia.

How is zuclopenthixol dissolved in coconut oil?

Both esters of zuclopenthixol are dissolved in fractionated coconut oil and when injected i.m., diffuse slowly from the oil depot to the body water phase where they are rapidly hydrolyzed to the active substance, zuclopenthixol. Once hydrolyzed, zuclopenthixol is distributed, metabolized and excreted as described.