What is acanthosis in esophagus?

Specialty. Gastroenterology. Glycogenic acanthosis are small raised white plaques commonly seen in the esophageal mucosa. It is seen incidentally in 3.5% of gastroscopies.

What is glycogenic acanthosis of esophagus?

Glycogenic acanthosis of the esophagus is a common benign entity, characterized by multifocal plaques of hyperplastic squamous epithelium with abundant intracellular glycogen deposits.

What is diffuse Glycogenic acanthosis?

Glycogenic acanthosis (GA) is a benign lesion frequently seen in upper endoscopy but with unknown clinical significance. Glycogenic acanthosis is reported as an incidental finding in 3.5% of endoscopies and is a diffuse benign oesophageal lesion easily recognised by experienced endoscopists.

What is basal cell hyperplasia of the esophagus?

Definition. A reactive (non-neoplastic) hyperplastic process affecting the esophageal squamous epithelium that is caused by inflammation. Morphologically it involves more than 15% of the thickness of the esophageal squamous epithelium.

What causes Glycogenic acanthosis?

Background/aims: Glycogenic acanthosis is described as benign thickening of the esophageal squamous epithelium of unknown etiology. Although its etiology is unknown, it has been reported that glycogenic acanthosis may be related to gastroesophageal reflux and hiatal hernia.

What is hyperplastic squamous epithelium?

Squamous hyperplasia is characterized by increased numbers of squamous cells resulting in increased thickness of the squamous epithelium, which may be diffuse or plaque-like or form blunt papillary projections. Hyperkeratosis is frequently seen with squamous cell hyperplasia.

What is squamous papilloma of the esophagus?

Esophageal squamous papilloma (ESP) is a rare benign epithelial tumor that is usually asymptomatic but can present with pyrosis and epigastric discomfort with or without dysphagia. In a study by Mosca and colleagues, papilloma was incidentally found in 9 patients, and no patients were reported to have dysphagia.

What is squamous epithelium in esophagus?

The inner lining of the esophagus is known as the mucosa. It is called squamous mucosa when the top layer is made up of squamous cells. Squamous cells are flat cells that look similar to fish scales when viewed under the microscope. Most of the esophagus is lined by squamous mucosa.

What is squamous epithelium?

In epithelium. Squamous, or flattened, epithelial cells, very thin and irregular in outline, occur as the covering epithelium of the alveoli of the lung and of the glomeruli and capsule of the kidney.

What is hyperplastic squamous esophageal mucosa?

Hyperplastic polyps of the esophagus and esophagogastric junction region (EGJ) are uncommon lesions characterized by hyperplastic epithelium (foveolar-type, squamous, or both) with variable amounts of inflamed stroma.

What does squamous papilloma look like?

Clinical features of squamous cell papilloma Less keratinised lesions are pink or red in colour and resemble a raspberry, whilst heavily keratinised lesions are white and look like the head of a cauliflower.

Can acid reflux cause papilloma?

Conclusion: The clinical course of these patients suggests a link between the presence of EERD and RRP. The inflammation induced by chronic acid exposure may result in the expression of HPV in susceptible tissues.

Is glycogenic acanthosis a disease of the esophagus?

Benign glycogenic acanthosis lesions of the esophagus Our results suggest that glycogenic acanthosis is primarily an age-related disease. We demonstrated that glycogenic acanthosis may be associated with gastroesophageal reflux and hiatal hernia. Further studies are necessary to confirm these findings.

What is the pathophysiology of glycogenic acanthosis?

Glycogenic acanthosis is a benign thickening of the esophageal squamous epithelium (surface cell lining) characterized by the presence of numerous, uniformly grey-white plaques made up of large squamous cells filled with glycogen.

What does a well-distended esophagus look like on Xray?

On x-ray views of the well-distended esophagus, the plaques appear as a finely nodular or cobblestone mucosal pattern. The findings are not associated with mucosal ulcerations, luminal narrowing, or mobility disturbance, although some patients may have coexistent hiatal hernia and gastroesophageal reflux. 2